Bromocriptine
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Bromocriptine is prevelant in the anti-aging scene as it's primary use is the inhibition of Prolactin; this hormone is one of the few that actually appears to increase with age. Prolactin is produced by the pituitary gland and its release is inhibited by Bromocriptine. Prolactin has been described as a “fat synthesis hormone” because one of its primary functions is to trigger lactation, (milk production...gyno in males) and weight gain in pregnancy. In men it helps to reduce serum Prolactin levels in men (although the precise role of Prolactin in men is unclear). A further possible need to control age-related Prolactin levels is offered by some researchers who believe that Prolactin is an immune system suppressant. Bromocriptine also affects the most famous of all pituitary hormones- Growth Hormone (GH). Bromocriptine increases GH secretion in individuals with low or normal GH concentrations, but paradoxically suppresses GH secretion in some patients with acromegaly, (a condition of excessive-production of GH). Studies indicate that Bromocriptine does not affect the release of any other anterior pituitary hormones. Due to its Dopamine enhancement, Bromocriptine has even been cited as an aphrodisiac, although little effort has been made to study and confirm this action. There have been several reports of “better controlled” orgasms and “almost orgasms” before the real orgasm occurs. If any countries allow for more medical categories such as “weak orgasm syndrome” or perhaps, “clinical sex-drive loss” then Dopamine agonists such as Bromocriptine are going to receive a lot of attention from the pharmaceutical manufacturers, especially in the wake of Viagra (r) sales. Another interesting clinical study administered a component of tobacco called DMBA to rats at a level where it is known to be very effective in producing breast cancer. However, rats that had been pretreated with Bromocriptine completely avoided any cancer development. Bromocriptine therefore appears to also offer itself as a very potent free radical quencher. One of the most recent studies indicates that Bromocriptine may be a candidate for the treatment of Type-2 diabetes. This is because Bromocriptine has been shown to suppress lipogenesis and improve glucose tolerance and insulin resistance. One animal study suggested that a further action of Bromocriptine is to alter CNS (central nervous system), regulating metabolism and as such, has another important use in helping to prevent weight gain, (this would be in addition to its improvement of diabetic conditions). |